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KMID : 0374919940150040637
Inje Medical Journal
1994 Volume.15 No. 4 p.637 ~ p.642
A Study on the Captopril's Effect for the Control of Idiopathic Edema



Abstract
Background :
@EN Primary care physicians frequently meet the patients who complin of edema.
We carried out this study to evaluate the captopril's effect on edema control.
@ES Methods :
@EN There were 77 patients who had suffered from various types of edema among the patients who had visited the Family Medicine Clinic of Seoul Paik Hospital from November 1992 to August 1993. We took their medical history, perfomed physical
examination. and requested chest X-ray and laboratory tests such as CBC, serum BUN/Cr, Na/K, GOT/GPT, Albumin, HBsAg, TSH, Urinalysis with microscopic examination. Thereafter we could select idiopathic edema. And we prescibed captopril (25mg once
a
day
at morning) for case group, and placebo for control group. We evaluated the captopril's effect on edema through comparing the diurnal change of body weight between case group and control group by paired t-test.
@ES Results :
@EN Among 77 patients, women were 67 persons (87.0%). There were 13 patients (16.9%) who had organic problems such as chronic renal failure, liver disease. hypothyroidism, and so on.
There were 20 healthy people (31.3%) compolaining of edema whose range of diurnal body weight change was over 0.5 kg, 9 healthy ones (14.0%) complaining of edema whose range of diurnal body weight change was below 0.5 kg, and 35 (54.7%) healthy
people
complaining of edema whose body weight was not checked.
We evaluated the captopril's effect on edema through comparlnmg the diurnal change of body weight between case group and control group but there was no statistically significant difference between case group and placebo group.
@ES Conclusions :
@EN There were 16.9% organic causes among the patients who had complained of edema. We prescribed captopril to control of edema in case of idiopathic edema, but it was not effective.
KEYWORD
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